The cees dekker Diaries

The cees dekker Diaries

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2009, discovery of a new phenotype for microbes in slender nanofluidic slits; and first detection of local protein structures along DNA using stable-point out nanopores

It was only while in the 1990s however, when nanotechnology experienced advanced into a amount in which one molecules might be manipulated, that the 1st experimental gadgets started to look.

The next content are merged in Scholar. Their put together citations are counted only for the very first write-up.

Non-equilibrium folding of specific DNA molecules recaptured nearly a thousand situations in a very stable point out nanopore

This yielded a breakthrough. In just just a few months, we were in the position to measure transportation via someone single-walled carbon nanotube. Based upon reduced-temperature experiments by a superb PhD student in my team, Sander Tans (now a valued colleague and professor at Delft College of Technological innovation by having an Lively study lab at AMOLF in Amsterdam), we showed that carbon nanotubes ended up genuine quantum wires with really prolonged (micrometres) electronic coherence lengths — confirming theoretical predictions of metallic conduct.

Immediate immobilization of native yeast iso-1 cytochrome c on bare gold: rapidly electron relay to redox enzymes and zeptomole protein-movie voltammetry

We use nanofabricated microfluidic constructions to pattern spatial boundaries for microbes and biomimetic vesicles with reconstituted protein networks and this evaluate the basic function of spatial confinement at the molecular and mobile level. Our projects involve the next:

Researching DNA loop extrusion by SMC proteins for chromosome architecture with single-molecule assays.

2003, shown the primary biosensors produced out of a carbon nanotube; fixed the structure and mechanism of DNA repair proteins; and discovery of a completely new system for fabricating stable-condition nanopores for DNA translocation

one). The existing–voltage curves showed major modulations with gate voltage, even at room temperature, which was in step with band bending in a very ~0.six eV bandgap semiconducting nanotube. These information also showed the conductance may very well be modulated by 6 orders of magnitude by altering the gate voltage. The outcome of the do the job — a room-temperature transistor created from one carbon nanotube molecule — were being published in Nature in Could 1998.

FtsZ treadmilling is important for Z-ring condensation and septal constriction initiation in bacterial cell division

‘That issues the artificial mobile, as part of the Dutch BaSyC initiative. Craig Venter looked prime-down in All those times and identified about five hundred genes which might be minimally demanded to get a working cell. We wish to glimpse base-up: how can we move from a handful of molecules to a whole Organic process?

Electrical https://www.ceesdekker.net transportation in monolayers of phthalocyanine molecular wires and AFM imaging of only one wire bridging two electrodes

‘I am driven by question and concerns. On a material amount I obtain responses in physics, but I practical experience my deepest pleasure with God. That faith also drives my science And the way I cope with people.